Center for Clinical Investigation

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Chimezie Thomas-Ogbuji

Senior Research Associate, Medical Informatics Core

Office: WRB

Email: cut@case.edu

Phone: 216.368.7566

Website:



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Research Interests

  • Semantic Web applications in Medical Informatics
    • Infrastructure for EHRs and PCHRs
      • Patient-controlled encryption techniques in PCHR systems
    • RDF as knowledge representation for patient record content
      • Efficient SPARQL query evaluation over large patient RDF dataset
    • Logic-based RDF query mediation
      • RDF query mediation over native RDF patient datasets
      • RDF query mediation over relational patient data
  • Applied ontology
    • Ontology management
    • Ontology for clinical informatics
      • Ontologically grounded framework for clinical terminology
  • Content repository infrastructure
    • XML and RDF processing as content repository infrastructure

Selected Publications

    1. Ruttenberg A. et al., Advancing translational research with the Semantic Web. BMC Bioinformatics 2007, 8(Suppl 3):S2. PMC1892099
    2. Ogbuji C.; “Infix OWL: An Idiomatic Interface for OWL.” Proceedings of Workshop on OWL: Experiences and Directions. Karlsruhe, Germany. October 2008. infixOwl.pdf
    3. Ogbuji C.; “Clinical Data Acquisition, Storage and Management.” In L. Liu, & T. Ozsu (Eds.), Encyclopedia of Database Systems. Springer 2009.
    4. Elliott B., Cheng E., Ogbuji C., Ozsoyoglu Z.M., “A Complete Translation from SPARQL into Efficient SQL.” Proceedings of the International Database Engineering and Applications Symposium. September 2009. p31-elliott.pdf
    5. Ogbuji C., Arabandi S., Zhang S., & Zhang G.Q., “Segmenting and Merging Domain-specific Ontology Modules for Clinical Informatics.” In A. Galton, & R. Mizoguchi (Eds.), Frontiers in Artificial Intelligence and Applications: Formal Ontology in Information Systems - Proceedings of the Sixth International Conference (FOIS 2010) (pp. 414 - 428). Amsterdam, Netherlands: 2010. DOI Web Link
    6. Luciano S. et al., “The Translational Medicine Ontology and Knowledge Base: driving personalized medicine by bridging the gap between bench and bedside.” Journal of Biomedical Semantics. 2011. open access
    7. Ogbuji C., “A Role for Semantic Web Technologies in Patient Record Data Collection.” In D. Wood (Eds.), Linking Enterprise Data. Springer 2010. led-ogbuji.html
    8. Ogbuji C., Gomadam K., Petrie C., "Web Technology and Architecture for Personal Health Records." . IEEE 2011. DOI